Pernem is a northmost administrative region or sub-district in North Goa in India.

Pernem is counted as belonging to one of the two Goan sub-regions, the Novas Conquistas, or New Conquests.

Sawantwadi was a state on Goa's northern border that allied sometimes with the Portuguese and sometimes with the Marathas.

The proposed Manohar International Airport is situated at Mopa in Pernem sub-district.

National Highway 17 (NH-17), which connects Mumbai (Bombay) and Goa, passes through Pernem (bypassed at Malpem) At the time of the 2011 Census of India, Pernem had a population of 75,747 with sex ratio of 960 females to 1000 males.

A Chapel in Pernem was built in 1852 by the Portuguese after their successful Novo Conquistas campaign.

Pedne hosts a very popular annual fair on Kojagiri poornima at Shri Bhagavati Temple premises.

This sub-district plays a major part in tourism of North Goa district.

It was basically a Guest house for Europeans visiting the northern frontier of Goa.

Towns in the district include: Mandrem, Morjim, Arambol, Parcem Villages in the district include: Agarvado, Alorna, Amberem, Cansarvornem, Casnem, Chandel, Chopdem, Corgão, Dargalim, Ibrampur, Mopa, Ozorim, Paliem, Pernem, Poroscodem, Querim, Tamboxem, Tiracol, Torxem, Tuem, Uguem, Varconda, Virnora.