Persona includes a mix of Latifah rapping and singing and features guest verses by Missy Elliot, Marsha Ambrosius, Shawn Stockman of Boyz II Men, Busta Rhymes, and Mary J. Blige.

Dre lent his vocals for another track titled, "Hard to Love Ya" alongside Busta Rhymes and Boyz II Men's Shawn Stockman.

On July 26, 2009, on her Twitter page, Latifah revealed that the second single from the album would be "Fast Car", which included a remix with Missy Elliot and Lil' Kim.

[7] Boston Globe critic Ken Capobianco that "Queen Latifah puts the torch songs aside and aims at burning up the clubs with this set of tuneful, briskly executed songs, almost exclusively produced by the superb Cool & Dre [...] For all the pleasures, Latifah sounds too guarded.

"[11] Allison Stewart from The Washington Post noted that "Latifah is usually a towering presence capable of dominating – and redeeming – even the iffiest tracks, but she's operating at a dimmer wattage here.