Born in Bangkok, Osathanugrah graduated in marketing from Southern Illinois University, and then worked in the advertising sector of his family-owned beverage company Osotspa, of which he later become CEO.

[1][2] In 1987, he got a large success as a singer with the pop song "เพียงชายคนนี้ (ไม่ใช่ผู้วิเศษ)"/ "I'm just a man (Mai Chai Phoo Wiset)".

[1][3] Osathanugrah also served as president of Bangkok University, where he opened the courses to new disciplines and innovative subject areas like digital marketing, financial and investment planning, video games and interactive media production, event management.

[1] An avid art collector whose collection includes paintings by Damien Hirst and Pablo Picasso, Osathanugrah founded the Dib Bangkok Museum of Contemporary Art, which is set to open in March 2025.

[4] Suffering from iron overload and diabetes, he died in his sleep on 14 August 2023, at the age of 68.