Here, he had the opportunity of working under Sir Hugh Cairns (surgeon) as a neuropathologist and perfected brain-cuts.
His expertise lay in the diagnosis of Brain tumors diseases of the nervous system.
He demonstrated muscle-spindles in eye muscles, and investigated single-neurone discharges from the optical cortex.
Many years before BSE in cattle and prions came to prominence, he studied scrapie and kuru and recognised that these diseases were transmitted by an agent not destroyed by heat.
[1] He was a founder-member of the Royal Colleges of Pathology and Psychiatry, and was a long-term member of the Physiological Society.