Ndegwa joined East African Breweries (EABL) in 2004 as the director of strategy, based in Nairobi, Kenya's capital city.
After eight years at EABL, he was appointed as the Managing Director of Guinness Ghana Breweries Limited (GGBL), in December 2011.
[5] Partly on account of his successes in Ghana and Nigeria, in July 2018, he was appointed General Manager of Diageo’s business in Western and Eastern Europe, including Russia.
[3][6] On 24 October 2019, the board of directors of Safaricom appointed Peter Ndegwa as the next CEO, effective 1 April 2020.
[9] Ndegwa is the next substantive CEO at Safaricom, since the death of Bob Collymore, who died on 1 July 2019.