He also became a partner in Reinhard Iselin's calico factory in Klampenborg which was relocated to Østerbro in 1766.
In 1779, Tutein was granted a license to establish a silk ribbon factory on Blågård in Nørrebro but gave up the plans and sold the property to the government later that same year.
By the late 1780s, his company had grown to become the third largest trading house in Copenhagen, surpassed only by those of Niels Ryberg and Frédéric de Coninck.
He died on 7 December 1799 and was buried in Assistens Cemetery but his remains were later moved to Hvedstrup Church.
The son, Friederich Tutein, continued the family's trading house under the name Fr.
Another daughter, Pauline Dorothea Tutein (31 March 1764 – 18 April 1814), married Hartvig Marcus Frisch.