A pioneer of the field of the portolan chart, he influenced Italian and Catalan mapmaking throughout the fourteenth and fifteenth centuries.

He also produced progressively more accurate depictions of the coastlines of northern Europe, in particular that of Britain and, to a lesser extent, Ireland.

There is also an atlas (1321) and a solitary portolan chart (1327) signed by "Perrino Vesconte", assumed to be either Pietro himself or possibly a younger relative member of his family using a diminutive form of 'Pietro'.

[3] Pietro Vesconte brought his experience as a maker of portolans to bear on the mappa mundi (circular world map) he produced, which introduced a previously unheard of accuracy to the genre.

[3] There are three known copies of Sanuto's Liber (c. 1320–21, c. 1321, c. 1325) that include Vesconte's maps, only the first of which is signed; the latter two are confidently assumed to have been done by him, or at least under his direction.