[2] After completing high school, Stone went on to Goucher College in the United States for her undergraduate degree from 1910 to 1914, where she graduated with honors.

[6] This reinforced Stone's interest in the medical field and spurred her on to the Johns Hopkins University School of Medicine, where she had won a prestigious fellowship.

[5][6] During Stone's time at the Danforth Hospital, she attended to patients, oversaw and taught the nurses, and spread awareness about both western medicine and Christianity.

Outside of the hospital, Stone continued practicing Christianity, becoming president of the Epworth League, an association for young adult Methodists, in 1919.

At the Bethel Misison, Stone was able to have more control of her responsibilities and finances all while continuing her medical work in the hospital and evangelism through the mission's church.

She died in May 1930, and her last rites and funeral service was held in the Bethel Tabernacle and Huangjao Cemetery, where "upwards of a thousand people" gathered to mourn her death.