Cooke) H. Perdomo, D. García, Gené, Cano & Guarro (2013) Phialemonium curvatum is a pathogenic fungus in the phylum Ascomycota.
[2] Phialemonium curvatum is typically found in a variety of environments including air, soil, industrial water and sewage.
[12] In reference specifically to P. curvatum, hypopyon (an accumulation of pus) as well as vitreous opacities are visible in patients with endophthalmitis.
[11][13] Histological findings documented in the case study by Weinberger et al. include: necrotizing granulomata, chronic lymphocytic infiltration and fine septate hyphae.
[4] To treat patients with this type of infection, they are put on antifungal medications such as: amphotericin B, ketoconazole, flucytosine and fluconazole until repeated peritoneal fluid cultures show no fungal growth.
[4] The subcutaneous infection caused by P. curvatum commences by forming a small cyst, less than one centimeter in diameter, which is not normally fixed to the skin.
[4] At the centre of the granulomata, it is also possible to identify microabscesses, collagen tissue as well as necrotic debris caused by the fungal hyphae.
[3][10] There was a report of P. curvatum affecting the lower spine and respiratory system and causing an abscess with purulent material in the middle.
[15][16][17] The course of treatment included antifungal medications, such amphotericin B, flucytosine, fluconazole, itraconazole, voriconazole and caspofungin, as well as removal of the cyst.