He was born in Uccle on 6 February 1638 as the eldest son of Gilles van der Noot, Lord of Carloo.

His brother, Roger-Wauthier van der Noot, 1st Baron of Carloo was Mayor of Brussels.

After his ordination, he was made a canon and eventually became Archpriest of the Chapter of St. Rumbold's Cathedral in Mechelen.

In Ghent he erected the chapel in Honour of Saint Amandus on the Campo Santo, and began renovations to the diocesan seminary.

His baroque tomb was designed by Jan-Baptist Helderberghe, Jan Boeksent and Pieter de Sutter.