Phosalacine is a natural antimicrobial and herbicidal compound that has been isolated from the Actinobacteria Kitasatosporia phosalacinea.

[1] It is a tripeptide consisting of the amino acids glufosinate (phosphinothricin), alanine, and leucine.

[2] It is similar in structure to bialaphos, differing by replacement of the terminal alanine with leucine.

Phosalacine has antimicrobial activity against Gram-positive and Gram-negative bacteria and some fungi.

[1] It is believed that the herbicidal activity is due to the slow release of glufosinate,[3] which is a commercially-used broad spectrum herbicide.