She graduated from Loyola University of the South's College of Music and made her professional debut with the New Orleans Opera Association as Flora Bervoix, in La traviata, in 1980.
[2] In 1997, Treigle portrayed the title role in the original version of Cherubini's Médée for Opera Quotannis at Alice Tully Hall, Lincoln Center in New York City.
[3] As of 2016[update], Treigle is Chair of Vocal Music at the New Orleans Center for Creative Arts (NOCCA).
After an hiatus of some ten years, she returned to the stage in the cameo role of Annina in La traviata, for the New Orleans Opera, in April 2009.
She portrayed Marthe Schwertlein in Faust for the same company in 2017 with Paul Groves in the name part, and she opened their 2017/2018 season as Lucia in Cavalleria rusticana.