Physiological Reports is a peer-reviewed open access online-only scientific journal covering original research in all areas of physiology.

It is published by Wiley-Blackwell on behalf of The Physiological Society and the American Physiological Society.

Susan Wray (University of Liverpool) was the first editor-in-chief until 2017 .

As well as receiving direct submissions, the journal has manuscripts "cascaded" to it from the journals of its owner societies (American Journal of Physiology, Experimental Physiology, and The Journal of Physiology).

Since 2015 it has also received papers cascaded by Acta Physiologica, a publication of the Scandinavian Physiological Society.