Physopyxis ananas is a species of thorny catfish found in the lowlands of the Essequibo and Amazon basins.

It is found in the countries of Brazil, Guyana, Peru and Venezuela.

This species grows to a length of 2.2 centimetres (0.87 in) SL.

They prefer to live in submerged organic litter in shallow waters.

This family Doradidae article is a stub.