The stop is located in the urban track of Rome, in Piazza Euclide, in the quarter Pinciano on the border with the quarter Parioli; it is accessed from one of the buildings located on the square, on the corner with Via Civinini, in front of the Basilica of the Immaculate Heart of Mary.

[2] It is one of the stops of the line that record the most traffic, since it is located in a densely inhabited area with a high number of offices.

In 1947 the city administration of Rome requested the construction of a stop on the underground section of the Rome–Civitacastellana–Viterbo railway, then under renovation to double it.

The location of Piazza Euclide was chosen, since it represented an important traffic junction for the quarters Flaminio and Parioli.

[1] In the summer of 2009 the station was closed due to renovation and upgrading works that affected the whole urban section of the line; during the approximately 70 days of interruption, the platforms were raised to achieve the ground-level boarding; furthermore, the architectural barriers were eliminated thanks to the installation of stairlifts and the creation of guided paths for partially sighted people.