A verbal clause stipulated that below the meridian of El Hierro, called the Line of Friendship, force would decide sovereignty and war could reign without affecting the peace between the nations in Europe.

[4] The Twelve Years' Truce signed in 1609 between the Netherlands and Spain, mediated by England and France, allowed the development of navigation to the Caribbean.

In 1623, a race against a Spanish Galleon backfired on the pirate, who found refuge on Saint Kitts where 400 British colonists had just arrived.

In 1626 he returned to France, where he won the support of Cardinal Richelieu to establish French colonies in the region by convincing him of the opportunity for profitable cultivation of tobacco, sugar cane, achiote, and indigo.

Trade with foreign slave ships, though illegal, was tolerated by colonial authorities in the face of the rising demand for labor.

The company tasked Jean du Plessis d'Ossonville and Charles Liénard de L'Olive with the colonization of Guadeloupe.

Having spent six months on Martinique, D'Esnambuc returned to Saint Christopher, where he soon died of illness, according to Jean-Baptiste Du Tertre.

A statue of the adventurer was erected in the Place de la Savane in Fort-de-France in 1935, on the occasion of the tricentennial of his taking of Martinique on behalf of King Louis XIII.

A banana boat in the service of the Compagnie Générale Transatlantique (acquired from Norway) bore his name from 1939 until 1942, when it was commandeered by the Kriegsmarine, repurposed as a minelayer, and rechristened "Pommern".

A long road of his hometown in Allouville-Bellefosse, and the village hall at 20 rue Jacques Anquetil, facing the office of tourism, built in 1945 and completely renovated in 2017, bears his name.

For the Heritage Days of September 17 and 18 2016, the commune of Allouville-Bellefosse organized an exposition dedicated to the navigator in its church Saint-Quentin, as well as a conference on him given by Marie-José Mainot.