Charles made his professional debut in April 1922, as a light heavyweight, losing on points over four rounds to Maurice Hennaut.

[3] He made a successful defence of his Belgian title against Humbeeck in May 1927, but the following month suffered his first loss in almost a year when he was beaten on points by Phil Scott at the Royal Albert Hall.

[5] He beat Bud Gorman in June,[6] but suffered the second defeat of his spell in the US in August to Otto von Porat, also losing his last fight in America, George Godfrey knocking him out in the second round at the end of the month.

[11] In February 1930 he travelled to the US once again, to face NYSAC world light heavyweight champion Tommy Loughran, a fight he lost on points.

[12] Charles made two more successful defences of his European title, against Roberto Roberti and Piet van der Veer, before returning to the US for a further series of fights in 1931.