It is first mentioned in 1223, and was subsequently enlarged in 1330 and in 1387 when Pope Urban VI had a baptismal font installed in the church.
The 36 m-tall bell tower has square layout, and remains unclad and in brick, originally it was meant be covered with marble facing.
The Piazza in front of the Cathedral has various monuments including a statue depicting Grand Duke Leopold, the Hapsburg ruler of Tuscany, sculpted by Vincenzo Santini.
Much of the decoration dates from the reign of Christina, Grand Duchess of Tuscany, who in 1627 commissioned the restoration of the Collegiata to Florentine artists, who provided large devotional altarpieces and sculptures.
Other artists include painters Matteo Rosselli, Francesco Curradi, Jacopo Vignali, Pietro Dandini, Bastiano Bitozzi, Jacopo Chiavistelli, and Alessandro Cominotti, and the sculptors Giovan Battista Stagi, Stagio Stagi and Ferdinando Tacca.