[3][4] In the southern part of México, specifically Campeche and Mérida, the local name is Frescura.

The plant enjoys a thorough watering after the soil has been allowed to dry, and misting has been shown to be beneficial.

Direct sunlight causes the leaves to turn brown and fall off, so it prefers filtered light.

Pilea microphylla has been introduced to various tropical and subtropical regions around the world.

It is considered an invasive species in Australia, China, Diego Garcia, the Galapagos Islands, the Federated States of Micronesia, Fiji, French Polynesia, Guam, Hawaii, India, Indonesia, Japan, Kiribati, Marshall Islands, Nauru, New Caledonia, Niue, Palau, Papua New Guinea, the Philippines, Pitcairn Islands, Singapore, the Solomon Islands, Tonga, and Wallis and Futuna.