Pilot Knob (also, Avie Quah-la-Altwa, Ha-bee-co-la-la, and San Pablo) is a peak in Imperial County, California.

Pilot Knob was named for its prominence as a landmark for riverboat traffic in the 19th-20th centuries on the Colorado River which borders Winterhaven–Yuma.

Separated from the center of the Cargo Muchacho Mountains by 7 mi, the volcanic landform is at the base of alluvial fans.

The All American Canal is cut from the south border of Pilot Knob, and can be seen in aerial views traversing the Algodones Dunes to the west.

The Alamo Canal intake was placed at Pilot Knob due to the availability of a solid rock foundation for the head gate.