His father, Emilio (1890–1962) the youngest of five children, emigrated to the United States in 1911 and returned to Italy in 1915 to fight as a volunteer in the First World War.
After high school, in February 1943 Pirro Cuniberti received his draft notice and is sent to the 2nd Grenadier Regiment of Sardinia; fate will also intervene in the tragic days defending Rome.
1948 is also the year of the first post war Venice Biennale, where he finally saw Van Gogh's Chambre d'Arles and discovered Paul Klee, who become, from that moment on, the reference for his concept of form as infinite creative genesis and meets for the first time the works by Mark Rothko, Max Ernst and Henry Moore.
He married Lalla in 1955 and in December 1956, presented by Francesco Arcangeli [it], he inaugurated his first solo exhibition at Circolo di Cultura in Bologna.
In 1972, Enzo Biagi, director of the newspaper "Il Resto del Carlino" invited him to oversee the graphic layout of their publication.