Pisissarfik (old spelling Pisigsarfik) is a 1,220-metre-high (4,000 ft) mountain in the Sermersooq municipality, West Greenland.

At that time there were often conflicts with the local Inuit; it is believed that this fighting (along with changes in climate) was one of the reasons for the disappearance of Scandinavian settlers from the region, and eventually from the whole of Greenland.

An Inuk and a Viking are said to have climbed to the summit and held a shooting competition with bow and arrow on a seal pelt, stretched on a bank of the fjord.

However, scientists from the Danish National Museum, who examined the site between 1945 and 1952, found that they were in fact Inuit graves dating from the 16th to 17th century.

Pisissarfik played an important role in the Christianisation of the region in the 18th century: on Pentecost Sunday 1749 the first Deutsche Messe was celebrated at its foot.