Plaistow (/ˈplæstaʊ/, traditionally /-toʊ/) is a town in Rockingham County, New Hampshire, United States.

[1] The highest point in Plaistow is an unnamed summit at 384 feet (117 m) above sea level near the town's northern end.

Timberlane Regional High School has had noticeable success in music, theatrical performance, wrestling, and softball.

Timberlane students participating in the program start during the 11th grade and spend two to three periods a day at either Salem or Pinkerton.

Upon graduation, the participating students receive an associate's degree along with a high school diploma.

Local businesses and numerous large chain stores are located along Route 125, which has become known for problems with heavy traffic during weekday commuting and weekend shopping hours.

Route 125 intersects with Interstate 495 in Massachusetts 2 miles (3 km) south of the center of Plaistow.

New Hampshire Route 108 runs north to south along the eastern edge of Plaistow, just 0.1 miles (0.16 km) west of the Massachusetts border.

It leads west into Atkinson and terminates to the southeast at the Massachusetts border, where the road continues into Haverhill as North Main Street.