The Platino Award for Best Actor (Spanish: Premio Platino al mejor actor / Premio Platino a la mejor interpretación masculina) is one of the Platino Awards, Ibero-America's film awards presented annually by the Entidad de Gestión de Derechos de los Productores Audiovisuales (EGEDA) and the Federación Iberoamericana de Productores Cinematográficos y Audiovisuales (FIPCA).

It was first presented in 2014, with Mexican actor, Eugenio Derbez being the first recipient of the award, for his role as Valentín Bravo in Instructions Not Included.

No actor has won this award more than once while actors Alfredo Castro and Ricardo Darín have received the most nominations for this award with four each, followed by Javier Bardem, Antonio de la Torre, Javier Gutiérrez, Javier Cámara and Damián Alcázar with three each; and Daniel Giménez Cacho, Luis Tosar and Eduard Fernández, all three with two each.

2020 winner Antonio Banderas also received a nomination for the Best Actor for Pain and Glory at the 92nd Academy Awards.

In the list below the winner of the award for each year is shown first, followed by the other nominees.