Notable designers who have been affiliated with Plazm include David Carson, Art Chantry, Milton Glaser, Rebeca Mendez, Reza Abedini, Modern Dog, Scott Clum, John C. Jay, Bruce Licher, Frank Kozik, Pablo Medina, The Attik, Why Not Associates, and Ed Fella.
Contributing artists have included Raymond Pettibon, Todd Haynes, Storm Tharp, Guillermo Gómez-Peña, Yoko Ono, Michael Brophy, Seripop, Rankin Renwick, Susan Seubert, and Terry Toedtemeier.
The magazine has also run original pieces by interviewees, such as a handwritten fax-rant from Iggy Pop and faux McDonald's employment applications from Poison Ivy and Lux Interior of The Cramps.
The magazine's blog was launched in 2008 on plazm.com; local Portland newspaper The Oregonian wrote, "We always take Plazm's recommendations seriously" and "These guys are among the most creative characters in the city, though, and we've already bookmarked them."
Clients of Plazm design have included Nike, LucasFilm, ESPN, Burgerville, The Cooley Gallery, Portland Center Stage, Jantzen Swimwear, and MTV.
Co-founder and current principal Joshua Berger became known for his work in ecological concerns and recycling systems in the late 1980s and early 1990s, as noted by Oregon Business Journal and other magazines.