Plesiolena is a small genus of South American mygalomorph spiders in the family Actinopodidae.

It was first described by Pablo A. Goloboff and Norman I. Platnick in 1987,[2] and it has only been found in Chile.

[1] The name is a combination of "plesiomorphy" and the genus Missulena.

[2] As of November 2021[update] it contains only 2 species: P. bonneti and P.

This Actinopodidae-related article is a stub.