Ploaghe (Sardinian: Piàghe) is a comune (municipality) in the Province of Sassari in the Italian region Sardinia, located about 160 kilometres (99 mi) north of Cagliari and about 21 kilometres (13 mi) southeast of Sassari.

Ploaghe borders the following municipalities: Ardara, Chiaramonti, Codrongianos, Nulvi, Osilo, Siligo.

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