Plum Run is a 12.10 mi (19.47 km) long 2nd order tributary to Chartiers Run in Washington County, Pennsylvania.

Plum Run rises about 2 miles southwest of Venice, Pennsylvania, and then flows southeast to join Chartiers Run at Houston.

[3] Plum Run drains 4.07 square miles (10.5 km2) of area, receives about 39.2 in/year of precipitation, has a wetness index of 324.74, and is about 45% forested.

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