Poictesme (/pwɑːˈtɛm/) is a fictional country or province which forms the setting of the fantasy works of James Branch Cabell, known collectively as Biography of the Life of Manuel.

Poictesme and Lotharingia are two of the three kingdoms in a short story by Isaac Asimov, "Prince Delightful and the Flameless Dragon".

The graphic novel/webcomic Girl Genius makes a passing reference to a "Poictesme Province" within its own fantasy version of Europe, in the strip of March 31, 2014.

In Judith Tarr's novel Kingdom of the Grail, Poictesme is a region in the mystical land of Montsalvat, along with Lyonesse, Caer Sidi, and Carbonek.

"Maps of Poictesme," James Branch Cabell: Literary Life and Legacy, Virginia Commonwealth University Libraries