Pulitzer Prize winner Annie Dillard's popular memoir, An American Childhood, is set in Point Breeze during the 1950s.

Both of John Edgar Wideman's memoirs, Brothers and Keepers and Hoop Roots, use North Point Breeze's Westinghouse Park as a setting, as well as in his fictional Homewood Trilogy.

Point Breeze also runs catty-corner (without a direct border) with the Pittsburgh neighborhood of Larimer to the north at the intersection of Penn and Fifth Avenues (This intersection also serves as an east–west "diagonal" for the Pittsburgh neighborhoods of Shadyside and North Point Breeze).

Malcolm James McCormick (January 19, 1992 – September 7, 2018), known professionally as Mac Miller.

David McCullough (July 7, 1933 – August 7, 2022), noted historian and author, two-time winner of the Pulitzer Prize, was born and raised in Point Breeze.