Set in the fictional Hoenn region, the season follows the adventures of the ten-year-old Pokémon Trainer Ash Ketchum, and his electric mouse partner Pikachu as they collect Gym Badges so they can compete in the Hoenn League competition.

The Japanese opening song is "Advance Adventure" (アドバンスアドベンチャー, Adobansu Adobenchā) by GARDEN for 40 episodes.

The ending songs are "Because the Sky is There" (そこに空があるから, Soko ni Sora ga Aru Kara) by Toshiko Ezaki for 18 episodes, and "Polka O Dolka" (ポルカ・ドルカ, Poruka O Doruka) by Inuko Inuyama (Meowth) and Nolsol Chorus Group for 22 episodes, and the English opening song is "I Wanna Be a Hero" by David Rolfe.

"[3] In the United States, Viz Video and Ventura Distribution released the series on 8 VHS and DVD volumes from 2004-2005.

Viz Media and Warner Home Video released Pokémon: Advanced – The Complete Collection on DVD in the United States on May 16, 2017.