Building on the arguments levelled in his previous works, Latour argues that this distinction between facts and values is rarely useful and in many situations dangerous.

He claims that it leads to a system that ignores nature's socially constructed status and creates a political order without "due process of individual will".

Instead, he calls for a "new Constitution" where different individuals can assemble democratically without the definitions of facts and values influenced by current attitudes towards nature and scientific knowledge.

Latour describes an alternate set of rules by which this assembly, or collective as he calls it, might come together and be constituted.

Sal Restivo emphasises that the book is reproducing the insights from Science Studies, which Bruno Latour himself has greatly contributed to.