Ponchatoula High School is a public high school in unincorporated Tangipahoa Parish, Louisiana, United States, near Ponchatoula.

It is operated by the Tangipahoa Parish School System.

Ponchatoula High School is one of the largest high schools in the state of Louisiana by student enrollment.

Ponchatoula High athletics competes in the LHSAA.

Ponchatoula High School's colors are, green and white, instead of Tulane's green and sky blue.