Inspired by Disney films since the first grade, Greno started as a young boy writing and drawing comic books and strips.
[2] In 1996, during his junior year at Columbus College of Art and Design, he was hired by Walt Disney Feature Animation.
[2] In 2006, he took over a long-in-development project Tangled, based on the fairy tale Rapunzel and chose Byron Howard, with whom he had collaborated on Bolt and Super Rhino, as a directing partner.
Loosely based on the fairy tale of Jack and the Beanstalk, it was scheduled for a 2020 release.
[4][5] In February 2018, it was announced that Greno had signed a multi-year contract with Skydance Media to write and direct an animated film titled Pookoo, as well as consult on projects in development.