The high school has resided in 3 separate building over its history.

[6] In January 1998 Portage Central High School, along with Portage Northern High School, became an official International Baccalaureate (IB) World School, governed by the International Baccalaureate Organization.

During construction, some shop classes were held in Portage Central Middle School.

Music and social studies classes were held in the former Waylee Elementary.

[8] Central High is a member of the SMAC (Southwestern Michigan Athletic Conference).