[3] Portsmouth High School's faculty consists of 42 men and 70 women, 73% of whom hold a Master's degree or higher.

Due to this involvement, Portsmouth High has a very positive relationship with the city and greater seacoast region.

Portsmouth High School offers 192 courses within 18 departments with a variety of academic levels of difficulty.

Advanced Placement courses are offered in English Literature and Composition, European History, United States History, Calculus AB/BC, Biology, Physics B, Statistics, Spanish Language, and French Language.

[5] The Portsmouth High School Athletics Department holds many state championship titles.