Powells Creek is a 5.20 mi (8.37 km) long 3rd order tributary to the Hyco River in Person County, North Carolina.

It then flows east and turns southeast into Person County, North Carolina to join the Hyco River about 3 miles south-southwest of Harmony, Virginia.

[2] Powells Creek drains 8.89 square miles (23.0 km2) of area, receives about 45.9 in/year of precipitation, has a wetness index of 379.41, and is about 61% forested.

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