By virtue of its extensive network of tributaries, the river drains a large part of Vidarbha region in Maharashtra, as well as the southern slopes of the Satpura Range in southeast Madhya Pradesh.

This junction lies on the border between the states of Maharashtra and Telangana near Tumdi Hettty, Kouthala Mandal (near Sirpur (T)).

The Pranahita River follows a short course of 113 kilometers, strictly adhering to the boundary between Gadchiroli district in Maharashtra and Komaram Bheem Asifabad,Mancherial, Jayashankar Bhupalapally districts in Telangana.

The direction of flow is southward, unlike most rivers of the Deccan Plateau.

Along its course, the river is flanked by thick forests and harbors rich biodiversity of flora and fauna.