PredictProtein (PP) is an automatic service that searches up-to-date public sequence databases, creates alignments, and predicts aspects of protein structure and function.

Users send a protein sequence and receive a single file with results from database comparisons and prediction methods.

PP went online in 1992 at the European Molecular Biology Laboratory; since 1999 it has operated from Columbia University and in 2009 it moved to the Technische Universität München.

This implied that we focused on incorporating only high-quality methods, and tried to collate results omitting less reliable or less important ones.

The attempt to ‘pre-digest’ as much information as possible to simplify the ease of interpreting the results is a unique pillar of PP.