Prempeh College is a public secondary boarding school for boys located in Kumasi, the capital city of the Ashanti Region, Ghana.

In 2016, Prempeh College won the Toyota Innovation Award at the International Robofest World Championships held in Michigan, USA.

Although there were some delays due to the Second World War, Prempeh College was designed in 1948 by British modernist architects Maxwell Fry and Jane Drew.

[7] Compared to other works by Jane Drew in the Ashanti region, Prempeh College campus was designed to incorporate modernist refinements, as described by Lain Jackson and Jessica Holland in their book titled The Architecture of Edwin Maxwell Fry and Jane Drew: Twentieth Century Pioneer Modernism and the tropics.

According to the Ashanti Pioneer newspaper, the opening ceremony of Prempeh College was held on 5 February 1949, when Major C. O. Butler, the chief commissioner of Ashanti, said in an address: "There is a great and growing need for training men to take up posts of responsibility not just as clerks in offices but in Agricultural Education, Mining, Forestry, Architecture, Engineering and Building in the many other technical posts on the fulling of which by Africans the future development of Ashanti and the Gold Coast as a whole largely depends … We British from overseas are here to help you ultimately to administer the country yourselves … until you yourselves can provide the agriculturalists, engineers, the technicians and the tradesmen who can develop the natural resources of your country.

[9] The school uniform includes a green shirt with the college crest along with a brown short(Awura abena).