The Presbyterian Hospital Invitational Criterium, or Charlotte Criterium, is an annual criterium bicycle race along an 1.2 miles (2 km) course located in Uptown, Charlotte, North Carolina, United States.

Its $125,000 purse is the largest for this type of event in the United States.

[1] The race serves as a benefit for the Brain Tumor Fund of the Carolinas, and is an officially sanctioned race as part of the USA CRITS Tour.

[2] The race has a total distance of 50 miles (80 km).

[3] The women's criterium runs along the same course as the men's at a distance of 25 miles (40 km).