Ormiston College had been established in 1907 by Constance Wilson and her two sisters in Palmerston Street, North Perth.

She had also studied modern language at three European universities, and had taught for twelve years at Glasgow High School.

After considering several permanent locations for the school, it eventually settled on the purchase of William Gerald Lefroy's property on the corner of View and McNeil Streets, Peppermint Grove.

After modifications and additions to the property, all boarders were transferred from North Perth, and the first classes began on the new campus in July.

As with most Australian schools, PLC utilises a house system through which students participate in Inter-House activities and competitions.

Music PLC offers music ensembles to both junior and senior students, including a stage band, three concert bands, three string orchestras, several string quartets, a combined chorale with Trinity College, a combined string chamber orchestra with Scotch College as well as a combined symphonic wind ensemble and vocal ensemble with PLC's brother school, Scotch College.

[16] Sport The Presbyterian Ladies' College physical education programme provides students of all abilities with opportunities to partake in recreational activities such as yoga and aerobics, and team sports such as netball, basketball, cricket, tennis, hockey, volleyball, soccer, softball, rowing, and water polo.

[18] Some notable Old Collegians include: Academic Entertainment, media and the arts Law Medicine and science Sport