Prescott High School is comprehensive public junior/senior high school located in Prescott, Arkansas, United States.

The assumed course of study for students follows the Smart Core curriculum developed by the Arkansas Department of Education (ADE), which requires students complete at least 22 units to graduate.

Students engage in regular courses and exams and may take Advanced Placement (AP) coursework and exams with the opportunity for college credit.

The Prescott High School mascot and athletic emblem is uniquely known as the Curley Wolves with maroon and white serving as the school colors.

For 2020-2021, the Prescott Curley Wolves compete in interscholastic competition in the 3A Region 5 Conference administered by the Arkansas Activities Association including football, golf (boys/girls), cross country (boys/girls), basketball (boys/girls), competitive cheer, baseball, softball, tennis (boys/girls), and track and field (boys/girls).