Prince Friedrich Leopold of Prussia (German: Joachim Karl Wilhelm Friedrich Leopold; 14 November 1865 – 13 September 1931) was a son of Prince Frederick Charles of Prussia and Princess Maria Anna of Anhalt-Dessau, married in 1854.

On 24 June 1889, he married in Berlin Princess Louise Sophie of Schleswig-Holstein-Sonderburg-Augustenburg (8 April 1866 in Kiel – 28 April 1952 in Bad Nauheim), a sister of Empress Auguste Viktoria, wife of Emperor Wilhelm II.

In the same year promoted to Generalmajor, commander of the Gardes du Corps, a Cuirassiers regiment of the 1st Guards Cavalry Brigade.

Prinz Friedrich Leopold was the last patron of the Prussian freemasons from the House of Hohenzollern.

During the November Revolution 1918, he hoisted a red flag on his hunting lodge, Jagdschloss Glienicke, near Berlin.