In 1638 her family moved to Königsberg where she made contact with local group of poets led by Simon Dach.

However, Louise Charlotte and her parents decided in favour of prince of Courland Jacob Kettler.

Louise Charlotte is attributed to have had a large influence over the policy of state during the reign of her consort.

When in 1657 Swedes invaded in Courland Louise Charlotte managed to receive a promise from Swedish general Jakob De la Gardie to spare her manors and peasants.

The negotiations between Brandenburg, Russia, Sweden and Poland took place in Mitau during her de facto reign.