Princess Marie of the Netherlands (Dutch: Prinses Wilhelmina Frederika Anna Elisabeth Marie der Nederlanden, Prinses van Oranje-Nassau; 5 June 1841 – 22 June 1910) was the fourth child and younger daughter of Prince Frederick of the Netherlands and wife of William, 5th Prince of Wied.

Marie was born at Wassenaar, Netherlands, the fourth child and younger daughter of Prince Frederick of the Netherlands (1797–1881) second son of William I of the Netherlands, and his wife, Princess Louise of Prussia (1808–1870), daughter of Frederick William III of Prussia.

Princess Marie was diagnosed with profound hearing problems at an early age.

Her parents hoped to marry her to Albert Edward, Prince of Wales (later King Edward VII) but the Prince's mother, Queen Victoria opposed the match.

Marie married on 18 July 1871 in Wassenaar, William, Prince of Wied (1845–1907), brother of Queen Elisabeth of Romania and elder son of Hermann, Prince of Wied and his wife, Princess Marie of Nassau.