Some of his notable works are Oneness, The Foul Truth, Up-Close With Priyakanta Laishram, Spaced Out – Panthung Di Kadaaida!, Who Said Boys Can't Wear Makeup?, It's Not My Choice and I am Special.

He received recognition as Manipur's Rising Star by Asian News International, The Youngest Filmmaker 2009 by Nokia, and Youth Icon 2009 by Mongba Hanba Magazine.

'[2] Since the second stage of his career as a filmmaker, Laishram has gained recognition for drawing attention to social issues that are either shameful or taboo.

[6] His films are known for focusing on taboo subjects such as child abuse, male rape, LGBTQ issues, gender neutrality, and drug menace.

[7] In 2015, he wrote, edited, and directed the film It's Not My Choice, which stars Bishesh Huirem, the first Indian to represent India in Miss International Queen 2016, and depicts the story of a young transgender person named Sanathoi who is deprived of her basic rights.

The Sangai Express wrote, "Priyakanta Laishram's ability to maintain a straightforward and concise screenplay and dialogue without becoming didactic in conveying his intended message is truly praiseworthy.

[3] Later in the year, he featured in the Kangana Ranaut starrer The Bollywood Diva, a music video produced by All India Bakchod and directed by Tanmay Bhat.

[15] Apart from boys and men who wear make-up and gender neutral clothes in real life, Inder Bajwa (Former Top Model), Thounaojam Strela Luwang, Bala Hijam, Nimrit Kaur Ahluwalia, Peden Ongmu Namgyal (Miss Diva Supranational 2017) and other renowned faces were also featured in the film.

[21] In 2020, his talk-show Up-Close With Priyakanta Laishram was released on his YouTube channel, that raises various social issues including those pertaining to gender and LGBTQ.

[4] In 2021, his film Spaced Out – Panthung Di Kadaaida based on the topic of teen drug abuse was released and acclaimed by the critics.

Alongside Priyakanta, the film stars Maya Choudhury, Suraj Ngashepam and Sachinker Sagolsem in the lead roles.

"[2] The Frontier Manipur describes Priyakanta Laishram as "A Hidden Gem Of Manipuri Cinema", who breaks several barriers with his mere perspective and changing the narrative with his thought-provoking scripts.

[6] He is cited as the "Torchbearer Of Manipur Queer Cinema" by Northeast Now, who also calls him a rare creature who has mastered the art of using the cinematic medium to expose societal wrongdoings and malpractices in an industry replete with old school directors.

[9] In 2023, he made a statement about same-sex unions in India, saying that the legal system needed to be set up to protect and enhance human rights and promote marriage equality.

He stated that the lack of legal recognition of same-sex marriage denies social benefits and increases prejudice and violence.