Prizzi is a town and comune of 5,711 inhabitants in the Italian Metropolitan City of Palermo, on the island of Sicily.

It is located 84 km (52 mi) south of the city of Palermo at an altitude of 1045 m (3,428 ft) above sea level on a hill in the upper valley of the River Sosio.

Traces have been found of a small Elymian settlement, called Hippana or Hyppana, dating from the 8th-6th centuries BC on the nearby Montagna dei Cavalli.

This settlement was later rebuilt in the 4th century BC, by Hiero I of Syracuse, and subsequently inhabited by Carthaginians, Greeks, Arabs, and Romans.

The name Prizzi derives from the Greek Pyrizo, meaning "incendiary"[4] as in the context of sending smoke signals, referring to its origin as an important point for fighting off enemy invaders in Sicily.