Profundiconus neocaledonicus is a species of sea snail, a marine gastropod mollusk in the family Conidae, the cone snails and their allies.

[1][2] Like all species within the genus Profundiconus, these cone snails are predatory and venomous.

A total of 82 venom components were identified from Profundiconus neocaledonicus.

Their venom is distinct from other cone snails so they must be handled with caution.

This marine species occurs in the Pacific Ocean off the Norfolk Ridge (off New Caledonia)