Propyrotherium is an extinct genus of mammals, belonging to the order Pyrotheria.

From a comparison with its close relatives, it is supposed that it was a large herbivorous mammal, vaguely similar to an elephant and with massive limb ; it was decidedly smaller than Pyrotherium but still of considerable size, and it is supposed that it was at least two meters long.

It was endowed with incisors developed in elongated and forward pointed tusks, with a limited growth, and had large bilophodont molars.

Propyrotherium was first described by Florentino Ameghino in 1901, based on fossilized teeth found in Late Eocene rocks from the Chubut Province of Argentine Patagonia.

Later findings allowed to realize a complete dental series and to carry cladistic analyzes ; according to those researches, Propyrotherium was ranked as a basal member of the family Pyrotheriidae.